TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma.

Activating mutations in the TERT promoter were recently identified in up to 71% of cutaneous melanoma. Subsequent studies found TERT promoter mutations in a wide array of other major human cancers. TERT promoter mutations lead to increased expression of telomerase, which maintains telomere length an...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Klaus G Griewank, Rajmohan Murali, Bastian Schilling, Tobias Schimming, Inga Möller, Iris Moll, Marion Schwamborn, Antje Sucker, Lisa Zimmer, Dirk Schadendorf, Uwe Hillen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3832433?pdf=render
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker