Synthesis of Amino Core Compounds of Galactosyl Phytosyl Ceramide Analogs for Developing iNKT-Cell Inducers

1-Aminophytosphingosine and 6-aminogalactosyl phytosphingosine were prepared in 61% and 40% yield libraries with 44 carboxylic acids showed that a 4-butylbenzoic acid-derived product exe, respectively. Glycosylation using benzoyl-protected lipid resulted in better a-selectivity for ceramide analogs,...

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Detalhes bibliográficos
Main Authors: Chung-Shan Yu, Ho-Lein Huang, Kuo-Yen Liao, Kun-I Lin, Kee-Ching Jeng, Yi-Hsian Lin, Kai-Shiang Chang, Wen-Chin Su, Yin-Cheng Huang, Li-Wu Chiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2012-03-01
Colecção:Molecules
Assuntos:
phytosphingosine
library
cancer
immune
glycosylation
Acesso em linha:http://www.mdpi.com/1420-3049/17/3/3058/
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