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The role of TDP-43 mislocalization in amyotrophic lateral sclerosis
Abstract Since its discovery as a primary component in cytoplasmic aggregates in post-mortem tissue of patients with Amyotrophic Lateral Sclerosis (ALS), TAR DNA Binding Protein 43 kDa (TDP-43) has remained a central focus to understand the disease. TDP-43 links both familial and sporadic forms of A...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-08-01
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| Colecção: | Molecular Neurodegeneration |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13024-020-00397-1 |
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