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The role of TDP-43 in amyotrophic lateral sclerosis and frontotemporal dementia
PURPOSE OF REVIEW: We examine current evidence that the TAR DNA binding protein, TDP-43, plays a pathogenic role in both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). RECENT FINDINGS: TDP-43 was recently identified as the major pathological protein in sporadic ALS and in the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869081/ https://ncbi.nlm.nih.gov/pubmed/18989115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WCO.0b013e3283168d1d |
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