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Anchored design of protein-protein interfaces.

Few existing protein-protein interface design methods allow for extensive backbone rearrangements during the design process. There is also a dichotomy between redesign methods, which take advantage of the native interface, and de novo methods, which produce novel binders.Here, we propose a new metho...

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Hlavní autoři: Steven M Lewis, Brian A Kuhlman
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3117852?pdf=render
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