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Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody Responses

Despite extensive research, the development of an effective malaria vaccine remains elusive. The induction of robust and sustained T cell and antibody response by vaccination is an urgent unmet need. Chimeric virus-like particles (VLPs) are a promising vaccine platform. VLPs are composed of multiple...

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Autors principals: David J. Pattinson, Simon H. Apte, Nani Wibowo, Tania Rivera-Hernandez, Penny L. Groves, Anton P. J. Middelberg, Denise L. Doolan
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020-09-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/article/10.3389/fimmu.2020.564627/full
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