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Polyfunctional and IFN-γ monofunctional human CD4(+) T cell populations are molecularly distinct

Pathogen-specific polyfunctional T cell responses have been associated with favorable clinical outcomes, but it is not known whether molecular differences exist between polyfunctional and monofunctional cytokine-producing T cells. Here, we report that polyfunctional CD4(+) T cells induced during Pla...

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Publicado en:JCI Insight
Autores principales: Burel, Julie G., Apte, Simon H., Groves, Penny L., McCarthy, James S., Doolan, Denise L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291737/
https://ncbi.nlm.nih.gov/pubmed/28194431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87499
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