Reduced Plasmodium Parasite Burden Associates with CD38(+) CD4(+) T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production

Using a unique resource of samples from a controlled human malaria infection (CHMI) study, we identified a novel population of CD4(+) T cells whose frequency in the peripheral blood was inversely correlated with parasite burden following P. falciparum infection. These CD4(+) T cells expressed the mu...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Burel, Julie G., Apte, Simon H., Groves, Penny L., Klein, Kerenaftali, McCarthy, James S., Doolan, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035011/
https://ncbi.nlm.nih.gov/pubmed/27662621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005839
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