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Highly Sensitive Quantitative Real-Time PCR for the Detection of Plasmodium Liver-Stage Parasite Burden following Low-Dose Sporozoite Challenge

The pre-erythrocytic stages of Plasmodium spp. are increasingly recognised as ideal targets for prophylactic vaccines and drug treatments. Intense research efforts in the last decade have been focused on in vitro culture and in vivo detection and quantification of liver stage parasites to assess the...

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Detalhes bibliográficos
Main Authors: Schussek, Sophie, Groves, Penny L., Apte, Simon H., Doolan, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788780/
https://ncbi.nlm.nih.gov/pubmed/24098596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077811
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