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Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses

The development of vaccines against complex intracellular pathogens, such as Plasmodium spp., where protection is likely mediated by cellular immune responses, has proven elusive. The availability of whole genome, proteome and transcriptome data has the potential to advance rational vaccine developm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schussek, Sophie, Trieu, Angela, Apte, Simon H., Sidney, John, Sette, Alessandro, Doolan, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678182/
https://ncbi.nlm.nih.gov/pubmed/29118376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15354-0
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