Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8(+) T Cell Responses but Differ in Capacity to Induce CD4(+) T Cell Responses and Antibody Responses

Despite extensive research, the development of an effective malaria vaccine remains elusive. The induction of robust and sustained T cell and antibody response by vaccination is an urgent unmet need. Chimeric virus-like particles (VLPs) are a promising vaccine platform. VLPs are composed of multiple...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pattinson, David J., Apte, Simon H., Wibowo, Nani, Rivera-Hernandez, Tania, Groves, Penny L., Middelberg, Anton P. J., Doolan, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550421/
https://ncbi.nlm.nih.gov/pubmed/33133076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.564627
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