Chimeric Murine Polyomavirus Virus-Like Particles Induce Plasmodium Antigen-Specific CD8+ T Cell and Antibody Responses

An effective vaccine against the Plasmodium parasite is likely to require the induction of robust antibody and T cell responses. Chimeric virus-like particles are an effective vaccine platform for induction of antibody responses, but their capacity to induce robust cellular responses and cell-mediat...

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Main Authors: David J. Pattinson, Simon H. Apte, Nani Wibowo, Yap P. Chuan, Tania Rivera-Hernandez, Penny L. Groves, Linda H. Lua, Anton P. J. Middelberg, Denise L. Doolan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-06-01
Colecção:Frontiers in Cellular and Infection Microbiology
Assuntos:
malaria
vaccine
circumsporozoite protein
virus-like particle
murine polyomavirus
cellular immunity
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcimb.2019.00215/full
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