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Ups and Downs of Poised RNA Polymerase II in B-Cells.

Recent genome-wide analyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5' end of genes. This elevated Pol II presence at promoters, referred to here as Poll II poising, is mainly (but not exclusively) attributed to temporal pausing of transcription during early elon...

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Hlavní autoři: Phuong Dao, Damian Wojtowicz, Steevenson Nelson, David Levens, Teresa M Przytycka
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2016-04-01
Edice:PLoS Computational Biology
On-line přístup:http://europepmc.org/articles/PMC4831825?pdf=render
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