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Ups and Downs of Poised RNA Polymerase II in B-Cells.

Recent genome-wide analyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5' end of genes. This elevated Pol II presence at promoters, referred to here as Poll II poising, is mainly (but not exclusively) attributed to temporal pausing of transcription during early elon...

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Bibliografiska uppgifter
Huvudupphovsmän: Phuong Dao, Damian Wojtowicz, Steevenson Nelson, David Levens, Teresa M Przytycka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2016-04-01
Serie:PLoS Computational Biology
Länkar:http://europepmc.org/articles/PMC4831825?pdf=render
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