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Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation

In embryonic stem cells (ESCs), silent genes with major developmental functions display a unique epigenetic state in which strong and broad binding by Polycomb repressive complexes (PRCs) is accompanied by the presence of poised RNA polymerase II (RNAPII) and activating histone marks (e.g. H3K4me3)...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Syst Biol
Päätekijä: Rada‐Iglesias, Alvaro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658701/
https://ncbi.nlm.nih.gov/pubmed/29061670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177968
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