Functional association of Gdown1 with RNA polymerase II poised on human genes

Most human genes are loaded with promoter proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, a protein that renders Pol II responsive to mediator, is involved in Pol II elongation control. During i...

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Bibliografiske detaljer
Main Authors: Cheng, Bo, Li, Tiandao, Rahl, Peter B., Adamson, Todd E., Loudas, Nicholas B., Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J., Hu, Xiaopeng, Gnatt, Averell, Young, Richard A., Price, David H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259526/
https://ncbi.nlm.nih.gov/pubmed/22244331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.022
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