Functional association of Gdown1 with RNA polymerase II poised on human genes

Most human genes are loaded with promoter proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, a protein that renders Pol II responsive to mediator, is involved in Pol II elongation control. During i...

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Detalhes bibliográficos
Main Authors: Cheng, Bo, Li, Tiandao, Rahl, Peter B., Adamson, Todd E., Loudas, Nicholas B., Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J., Hu, Xiaopeng, Gnatt, Averell, Young, Richard A., Price, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259526/
https://ncbi.nlm.nih.gov/pubmed/22244331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.022
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