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Regulation of RNA Polymerase II Termination by Phosphorylation of Gdown1

Gdown1 is a substoichiometric subunit of RNA polymerase II (Pol II) that has been recently demonstrated to be involved in stabilizing promoter-proximal paused Pol II. It was shown to inhibit termination of Pol II by transcription termination factor 2 (TTF2) as well as block elongation stimulation by...

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Bibliografiske detaljer
Main Authors: Guo, Jiannan, Turek, Michael E., Price, David H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007455/
https://ncbi.nlm.nih.gov/pubmed/24634214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537662
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