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Functional association of Gdown1 with RNA polymerase II poised on human genes
Most human genes are loaded with promoter proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, a protein that renders Pol II responsive to mediator, is involved in Pol II elongation control. During i...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259526/ https://ncbi.nlm.nih.gov/pubmed/22244331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.022 |
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