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Ups and Downs of Poised RNA Polymerase II in B-Cells.

Recent genome-wide analyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5' end of genes. This elevated Pol II presence at promoters, referred to here as Poll II poising, is mainly (but not exclusively) attributed to temporal pausing of transcription during early elon...

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Bibliografiske detaljer
Main Authors: Phuong Dao, Damian Wojtowicz, Steevenson Nelson, David Levens, Teresa M Przytycka
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-04-01
Serier:PLoS Computational Biology
Online adgang:http://europepmc.org/articles/PMC4831825?pdf=render
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