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Ups and Downs of Poised RNA Polymerase II in B-Cells.

Recent genome-wide analyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5' end of genes. This elevated Pol II presence at promoters, referred to here as Poll II poising, is mainly (but not exclusively) attributed to temporal pausing of transcription during early elon...

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Autors principals: Phuong Dao, Damian Wojtowicz, Steevenson Nelson, David Levens, Teresa M Przytycka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2016-04-01
Col·lecció:PLoS Computational Biology
Accés en línia:http://europepmc.org/articles/PMC4831825?pdf=render
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