METTL5 in physiology and pathology: mechanisms and implications
METTL5, in complex with TRMT112, catalyzes N6-methyladenosine (m6A) at A1832 of 18S rRNA, acting as a novel regulator of translational control. This modification within the ribosomal decoding center modulates ribosome assembly and selective mRNA translation. Physiologically, METTL5 is required for e...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Frontiers Media S.A.
2025-12-01
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| Cyfres: | Frontiers in Cell and Developmental Biology |
| Pynciau: | |
| Mynediad Ar-lein: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1708541/full |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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