METTL5 in physiology and pathology: mechanisms and implications
METTL5, in complex with TRMT112, catalyzes N6-methyladenosine (m6A) at A1832 of 18S rRNA, acting as a novel regulator of translational control. This modification within the ribosomal decoding center modulates ribosome assembly and selective mRNA translation. Physiologically, METTL5 is required for e...
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| Автори: | , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2025-12-01
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| Серія: | Frontiers in Cell and Developmental Biology |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1708541/full |
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