METTL1 mediated tRNA m7G modification promotes leukaemogenesis of AML via tRNA regulated translational control
Abstract Background RNA modifications have been proven to play fundamental roles in regulating cellular biology process. Recently, maladjusted N7-methylguanosine (m7G) modification and its modifiers METTL1/WDR4 have been confirmed an oncogene role in multiple cancers. However, the functions and mole...
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| Автори: | , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2024-01-01
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| Серія: | Experimental Hematology & Oncology |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s40164-024-00477-8 |
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