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METTL5 in physiology and pathology: mechanisms and implications

METTL5, in complex with TRMT112, catalyzes N6-methyladenosine (m6A) at A1832 of 18S rRNA, acting as a novel regulator of translational control. This modification within the ribosomal decoding center modulates ribosome assembly and selective mRNA translation. Physiologically, METTL5 is required for e...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chunhong Li, Xiulin Jiang, Yixiao Yuan, Qiang Wang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2025-12-01
Rangatū:Frontiers in Cell and Developmental Biology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fcell.2025.1708541/full
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