METTL5 in physiology and pathology: mechanisms and implications
METTL5, in complex with TRMT112, catalyzes N6-methyladenosine (m6A) at A1832 of 18S rRNA, acting as a novel regulator of translational control. This modification within the ribosomal decoding center modulates ribosome assembly and selective mRNA translation. Physiologically, METTL5 is required for e...
Sparad:
| Huvudupphov: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Frontiers Media S.A.
2025-12-01
|
| Serie: | Frontiers in Cell and Developmental Biology |
| Ämnen: | |
| Länkar: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1708541/full |
| Taggar: |
Inga taggar, Lägg till första taggen!
|