Analyses on clustering of the conserved residues at protein-RNA interfaces and its application in binding site identification

Abstract Background The maintenance of protein structural stability requires the cooperativity among spatially neighboring residues. Previous studies have shown that conserved residues tend to occur clustered together within enzyme active sites and protein-protein/DNA interfaces. It is possible that...

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Bibliografische gegevens

Hoofdauteurs:	Zhen Yang, Xueqing Deng, Yang Liu, Weikang Gong, Chunhua Li
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2020-02-01
Reeks:	BMC Bioinformatics
Onderwerpen:	Protein-RNA interfaces Conserved residues Clustering characteristics Hot spot residues Binding site identification
Online toegang:	http://link.springer.com/article/10.1186/s12859-020-3398-9
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