Analyses on clustering of the conserved residues at protein-RNA interfaces and its application in binding site identification

Abstract Background The maintenance of protein structural stability requires the cooperativity among spatially neighboring residues. Previous studies have shown that conserved residues tend to occur clustered together within enzyme active sites and protein-protein/DNA interfaces. It is possible that...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Zhen Yang, Xueqing Deng, Yang Liu, Weikang Gong, Chunhua Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2020-02-01
Цуврал:	BMC Bioinformatics
Нөхцлүүд:	Protein-RNA interfaces Conserved residues Clustering characteristics Hot spot residues Binding site identification
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12859-020-3398-9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!