Analyses on clustering of the conserved residues at protein-RNA interfaces and its application in binding site identification

Abstract Background The maintenance of protein structural stability requires the cooperativity among spatially neighboring residues. Previous studies have shown that conserved residues tend to occur clustered together within enzyme active sites and protein-protein/DNA interfaces. It is possible that...

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Prif Awduron:	Zhen Yang, Xueqing Deng, Yang Liu, Weikang Gong, Chunhua Li
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2020-02-01
Cyfres:	BMC Bioinformatics
Pynciau:	Protein-RNA interfaces Conserved residues Clustering characteristics Hot spot residues Binding site identification
Mynediad Ar-lein:	http://link.springer.com/article/10.1186/s12859-020-3398-9
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!