Lorcaserin improves glycemic control via a melanocortin neurocircuit

Objective: The increasing prevalence of type 2 diabetes (T2D) and associated morbidity and mortality emphasizes the need for a more complete understanding of the mechanisms mediating glucose homeostasis to accelerate the identification of new medications. Recent reports indicate that the obesity med...

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主要な著者:	Luke K. Burke, Emmanuel Ogunnowo-Bada, Teodora Georgescu, Claudia Cristiano, Pablo B. Martinez de Morentin, Lourdes Valencia Torres, Giuseppe D'Agostino, Christine Riches, Nicholas Heeley, Yue Ruan, Marcelo Rubinstein, Malcolm J. Low, Martin G. Myers, Justin J. Rochford, Mark L. Evans, Lora K. Heisler
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2017-10-01
シリーズ:	Molecular Metabolism
主題:	5-HT2c receptor Type 2 diabetes Hypothalamus Lorcaserin Pro-opiomelanocortin (POMC) Melanocortin4 receptor (Mc4r)
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2212877817304258
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