Lorcaserin improves glycemic control via a melanocortin neurocircuit

Objective: The increasing prevalence of type 2 diabetes (T2D) and associated morbidity and mortality emphasizes the need for a more complete understanding of the mechanisms mediating glucose homeostasis to accelerate the identification of new medications. Recent reports indicate that the obesity med...

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Prif Awduron:	Luke K. Burke, Emmanuel Ogunnowo-Bada, Teodora Georgescu, Claudia Cristiano, Pablo B. Martinez de Morentin, Lourdes Valencia Torres, Giuseppe D'Agostino, Christine Riches, Nicholas Heeley, Yue Ruan, Marcelo Rubinstein, Malcolm J. Low, Martin G. Myers, Justin J. Rochford, Mark L. Evans, Lora K. Heisler
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2017-10-01
Cyfres:	Molecular Metabolism
Pynciau:	5-HT2c receptor Type 2 diabetes Hypothalamus Lorcaserin Pro-opiomelanocortin (POMC) Melanocortin4 receptor (Mc4r)
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2212877817304258
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!