Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology

Abstract Background Genomic alterations in 8 genes are now the targets of FDA-approved therapeutics in non-small cell lung cancer (NSCLC), but their distribution according to genetic ancestry, sex, histology, and smoking is not well established. Methods Using multi-institutional genetic testing data...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Elio Adib, Amin H. Nassar, Sarah Abou Alaiwi, Stefan Groha, Elie W. Akl, Lynette M. Sholl, Kesi S. Michael, Mark M. Awad, Pasi A. Jӓnne, Alexander Gusev, David J. Kwiatkowski
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-04-01
Colecção:	Genome Medicine
Assuntos:	Non-small cell lung cancer Targeted therapies Targetable genomic alterations Genetic ancestry Smoking
Acesso em linha:	https://doi.org/10.1186/s13073-022-01041-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!