Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology

Abstract Background Genomic alterations in 8 genes are now the targets of FDA-approved therapeutics in non-small cell lung cancer (NSCLC), but their distribution according to genetic ancestry, sex, histology, and smoking is not well established. Methods Using multi-institutional genetic testing data...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Elio Adib, Amin H. Nassar, Sarah Abou Alaiwi, Stefan Groha, Elie W. Akl, Lynette M. Sholl, Kesi S. Michael, Mark M. Awad, Pasi A. Jӓnne, Alexander Gusev, David J. Kwiatkowski
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2022-04-01
Sarja:	Genome Medicine
Aiheet:	Non-small cell lung cancer Targeted therapies Targetable genomic alterations Genetic ancestry Smoking
Linkit:	https://doi.org/10.1186/s13073-022-01041-x
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