Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study

Abstract Background There is increasing need for effective incorporation of high-dimensional genetics data from individuals with varied ancestry in genome-wide association (GWAS) analyses. Classically, multi-ancestry GWAS analyses are performed using statistical meta-analysis to combine results cond...

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Detalhes bibliográficos

Principais autores:	Alan Kuang, Marie-France Hivert, M. Geoffrey Hayes, William L. Lowe, Denise M. Scholtens
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-01-01
coleção:	BMC Genomics
Assuntos:	Genome-wide association analysis Multi-ancestry Meta-analysis Mega-analysis
Acesso em linha:	https://doi.org/10.1186/s12864-025-11229-1
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