Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function
Complex lymphatic anomalies (CLAs) are sporadically occurring diseases caused by the maldevelopment of lymphatic vessels. We and others recently reported that somatic activating mutations in KRAS can cause CLAs. However, the mechanisms by which activating KRAS mutations cause CLAs are poorly underst...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2023-09-01
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| Seri Bilgileri: | Frontiers in Cell and Developmental Biology |
| Konular: | |
| Online Erişim: | https://www.frontiersin.org/articles/10.3389/fcell.2023.1276333/full |
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