Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution

Abstract Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Raphaël Mourad, Krzysztof Ginalski, Gaëlle Legube, Olivier Cuvier
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2018-03-01
Цуврал:	Genome Biology
Нөхцлүүд:	Double-strand breaks Epigenetics Chromatin Machine learning
Онлайн хандалт:	http://link.springer.com/article/10.1186/s13059-018-1411-7
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!