Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution
Abstract Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2018-03-01
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| Serier: | Genome Biology |
| Fag: | |
| Online adgang: | http://link.springer.com/article/10.1186/s13059-018-1411-7 |
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