Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution
Abstract Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2018-03-01
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| シリーズ: | Genome Biology |
| 主題: | |
| オンライン・アクセス: | http://link.springer.com/article/10.1186/s13059-018-1411-7 |
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