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Biliverdin reductase: more than a namesakeThe reductase, its peptide fragments and biliverdin regulate activity of the three classes of protein kinase C.

The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably umatched by any single protein. hBVR is a Ser/Thr/Tyr kinase, a scaffold protein, a transcription factor and an intracellular transporter of gene regulators. hBVR is an upstream activator of the insulin/IGF-1 signal...

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Principais autores: Peter E.M. Gibbs, Cicerone eTudor, Mahin D Maines
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2012-03-01
Serija:Frontiers in Pharmacology
Teme:
Online dostop:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00031/full
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