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Biliverdin reductase: more than a namesakeThe reductase, its peptide fragments and biliverdin regulate activity of the three classes of protein kinase C.

The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably umatched by any single protein. hBVR is a Ser/Thr/Tyr kinase, a scaffold protein, a transcription factor and an intracellular transporter of gene regulators. hBVR is an upstream activator of the insulin/IGF-1 signal...

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Autors principals: Peter E.M. Gibbs, Cicerone eTudor, Mahin D Maines
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012-03-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00031/full
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