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Biliverdin reductase: more than a namesakeThe reductase, its peptide fragments and biliverdin regulate activity of the three classes of protein kinase C.

The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably umatched by any single protein. hBVR is a Ser/Thr/Tyr kinase, a scaffold protein, a transcription factor and an intracellular transporter of gene regulators. hBVR is an upstream activator of the insulin/IGF-1 signal...

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Autores principales: Peter E.M. Gibbs, Cicerone eTudor, Mahin D Maines
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2012-03-01
Colección:Frontiers in Pharmacology
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Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00031/full
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