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Biliverdin reductase: more than a namesakeThe reductase, its peptide fragments and biliverdin regulate activity of the three classes of protein kinase C.

The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably umatched by any single protein. hBVR is a Ser/Thr/Tyr kinase, a scaffold protein, a transcription factor and an intracellular transporter of gene regulators. hBVR is an upstream activator of the insulin/IGF-1 signal...

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Autori principali: Peter E.M. Gibbs, Cicerone eTudor, Mahin D Maines
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2012-03-01
Serie:Frontiers in Pharmacology
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Accesso online:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00031/full
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