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Biliverdin reductase: more than a namesakeThe reductase, its peptide fragments and biliverdin regulate activity of the three classes of protein kinase C.

The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably umatched by any single protein. hBVR is a Ser/Thr/Tyr kinase, a scaffold protein, a transcription factor and an intracellular transporter of gene regulators. hBVR is an upstream activator of the insulin/IGF-1 signal...

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Auteurs principaux: Peter E.M. Gibbs, Cicerone eTudor, Mahin D Maines
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2012-03-01
Collection:Frontiers in Pharmacology
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Accès en ligne:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00031/full
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