HIV-1 gp120-induced lysosomal stress responses are controlled by TRPML1 redox sensors
Background Increased lysosomal stress responses (LSR) are commonly implicated in the pathogenesis of neurodegenerative disorders including HIV-1-associated neurocognitive disorders (HAND). The HIV-1 envelope glycoprotein gp120 causes LSR, increases levels of ferrous iron (Fe2+) in the cytosol and in...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis Group
2026-12-01
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| Serie: | Redox Report |
| Soggetti: | |
| Accesso online: | https://www.tandfonline.com/doi/10.1080/13510002.2026.2679333 |
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