Endolysosome Iron Chelation Inhibits HIV-1 Protein-Induced Endolysosome De-Acidification-Induced Increases in Mitochondrial Fragmentation, Mitophagy, and Cell Death

People with human immunodeficiency virus-1 (PLWH) experience high rates of HIV-1-associated neurocognitive disorders (HANDs); clinical symptoms range from being asymptomatic to experiencing HIV-associated dementia. Antiretroviral therapies have effectively prolonged the life expectancy related to PL...

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Bibliografische Detailangaben

Hauptverfasser:	Peter W. Halcrow, Nirmal Kumar, Darius N. K. Quansah, Aparajita Baral, Braelyn Liang, Jonathan D. Geiger
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-05-01
Schriftenreihe:	Cells
Schlagworte:	endolysosomes pH mitochondria autophagosomes mitophagy autophagy
Online-Zugang:	https://www.mdpi.com/2073-4409/11/11/1811
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