Mesoporous Polydopamine Nanoparticles Attenuate Morphine Tolerance in Neuropathic Pain Rats by Inhibition of Oxidative Stress and Restoration of the Endogenous Antioxidant System

Oxidative stress resulting from reactive oxygen species (ROS) is known to play a key role in numerous neurological disorders, including neuropathic pain. Morphine is one of the commonly used opioids for pain management. However, long-term administration of morphine results in morphine antinociceptiv...

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Үндсэн зохиолчид:	Yaswanth Kuthati, Prabhakar Busa, Srikrishna Tummala, Vaikar Navakanth Rao, Venkata Naga Goutham Davuluri, Yen-Peng Ho, Chih-Shung Wong
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-01-01
Цуврал:	Antioxidants
Нөхцлүүд:	morphine antinociceptive tolerance MPDA neuropathic pain morphine reactive oxygen species oxidative stress
Онлайн хандалт:	https://www.mdpi.com/2076-3921/10/2/195
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!