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Precise genome editing with base editors

Single-nucleotide variants account for about half of known pathogenic genetic variants in human. Genome editing strategies by reversing pathogenic point mutations with minimum side effects have great therapeutic potential and are now being actively pursued. The emerge of precise and efficient genome...

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Bibliografische gegevens
Hoofdauteurs: Liu Hongcai, Zhu Yao, Li Minjie, Gu Zhimin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: De Gruyter 2023-02-01
Reeks:Medical Review
Onderwerpen:
Online toegang:https://doi.org/10.1515/mr-2022-0044
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