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Precise genome editing with base editors

Single-nucleotide variants account for about half of known pathogenic genetic variants in human. Genome editing strategies by reversing pathogenic point mutations with minimum side effects have great therapeutic potential and are now being actively pursued. The emerge of precise and efficient genome...

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Detalles Bibliográficos
Principais autores: Liu Hongcai, Zhu Yao, Li Minjie, Gu Zhimin
Formato: Artigo
Idioma:Inglês
Publicado: De Gruyter 2023-02-01
Series:Medical Review
Assuntos:
Acceso en liña:https://doi.org/10.1515/mr-2022-0044
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