CRISPR-Variational Autoencoder: An Interpretable and Efficiency-Aware Guide Ribonucleic Acid Sequence Generator
Deep learning has shown significant potential in predicting guide Ribonucleic Acid (gRNA) efficiency, thereby optimizing engineered gRNAs and enhancing the application of CRISPR-Cas systems in genome editing. However, the black-box nature of these deep learning methods often lacks transparency, hind...
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| Format: | Artigo |
| Sprache: | Inglês |
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Engineered Science Publisher LLC
2025-03-01
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| Schriftenreihe: | Engineered Science |
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| Online-Zugang: | https://www.espublisher.com/journals/articlehtml/engineered-science/10.30919-es1452 |
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