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CRISPR-Variational Autoencoder: An Interpretable and Efficiency-Aware Guide Ribonucleic Acid Sequence Generator

Deep learning has shown significant potential in predicting guide Ribonucleic Acid (gRNA) efficiency, thereby optimizing engineered gRNAs and enhancing the application of CRISPR-Cas systems in genome editing. However, the black-box nature of these deep learning methods often lacks transparency, hind...

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Autors principals: Ahmad Obeid, Hasan AlMarzouqi
Format: Artigo
Idioma:Inglês
Publicat: Engineered Science Publisher LLC 2025-03-01
Col·lecció:Engineered Science
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Accés en línia:https://www.espublisher.com/journals/articlehtml/engineered-science/10.30919-es1452
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