Precise genome editing with base editors

Single-nucleotide variants account for about half of known pathogenic genetic variants in human. Genome editing strategies by reversing pathogenic point mutations with minimum side effects have great therapeutic potential and are now being actively pursued. The emerge of precise and efficient genome...

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Bibliografiska uppgifter

Huvudupphov:	Liu Hongcai, Zhu Yao, Li Minjie, Gu Zhimin
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	De Gruyter 2023-02-01
Serie:	Medical Review
Ämnen:	adenine base editor base editing clustered regularly interspaced short palindromic repeats (crispr)/ crispr-associated protein cytosine base editor
Länkar:	https://doi.org/10.1515/mr-2022-0044
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